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Journal of Advances in Medical and Biomedical Research ; 30(140):211-214, 2022.
Article in English | EMBASE | ID: covidwho-1822723

ABSTRACT

A number of studies have previously provided evidence on the Anti-inflammatory properties of plant-derived compounds that can prevent lung injury. In this study, we attempted to analyze the therapeutic effects of PM 014 on inflammation and pulmonary fibrosis in COVID-19 as well as describing the treatment of one of the most challenging problems related to the coronavirus-19 (COVID-19). We believe that having a close look at all angles of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies for providing an appropriate treatment.

2.
Med Hypotheses ; 143: 109871, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-343478

ABSTRACT

recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner and we describe one of the most challenging theories of immunotherapy in coronavirus-19 (COVID-19). The analysis of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies to provide anti-inflammatory drugs.


Subject(s)
Anti-Inflammatory Agents/administration & dosage , Coronavirus Infections/drug therapy , Coronavirus Infections/immunology , Immune System/drug effects , Immune System/virology , Nicotinic Agonists/administration & dosage , Pneumonia, Viral/drug therapy , Pneumonia, Viral/immunology , Anti-Inflammatory Agents/therapeutic use , Betacoronavirus , Biomarkers/metabolism , COVID-19 , Cholinergic Agents/therapeutic use , Coronavirus Infections/mortality , Cytokines/metabolism , Humans , Immunotherapy , Inflammation , Nicotine/metabolism , Pandemics , Pneumonia, Viral/mortality , Receptors, Nicotinic/metabolism , SARS-CoV-2 , Survivors , Treatment Outcome
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